The aim of this placebo-controlled study is to determine whether testosterone replacement therapy administered by transdermal gel can improve response to sildenafil (Viagra R) treatment in men with erectile dysfunction (ED) and low testosterone levels. In a randomized, double-blind, parallel, placebo-controlled trial, the combination of sildenafil with testosterone was not superior to sildenafil plus placebo in improving erectile function in men with erectile dysfunction and low testosterone levels.
Studies show that testosterone treatment does not help men with low testosterone if erectile dysfunction is the only symptom. Since testosterone is the main sex hormone for men, one might think that low testosterone is the main cause of erectile dysfunction.
After age 50, testosterone levels in men slowly decline and erectile dysfunction becomes more common. As men age, testosterone levels naturally decline gradually, which can cause some symptoms.
Due to the many side effects of low testosterone, such as low libido and depression, some men find it difficult to get or maintain an erection. Interestingly, other studies have also shown that men with low testosterone levels often report improved erections after testosterone treatment.
By optimizing your testosterone levels, you will alleviate the symptoms of low testosterone levels by improving erectile function. While our primary goal is to help you achieve optimal testosterone levels for long-term health, many men experience significant improvements in erectile function.
The mechanism by which testosterone plays a role in erectile function is not fully understood. Erection is largely dependent on testosterone; however, this relationship is complex and not fully understood. The relationship between low T erections and ED is androgen-dependent, but the relationship between the two is complex and not fully understood.
Low testosterone (hypogonadism) also plays a key role in sexual dysfunction (eg, low libido, poor erection quality, ejaculatory or orgasmic dysfunction, decreased spontaneous erection, or reduced sexual activity). One study examined the role of testosterone supplementation in men with hypogonadism and erectile dysfunction.
These results indicate that testosterone deficiency causes neurogenic dysfunction in erectile tissues; however, future research should uncover the mechanism by which testosterone acts on the nervous system. These results suggest that testosterone, in addition to its known action on the endothelium, may locally regulate erectile function by acting on human corpus cavernosum smooth muscle.
If you have erectile dysfunction with normal testosterone levels, you may see more improvement with erectile dysfunction medications. AA2500 Testosterone Gel normalizes androgen levels in older men, improving body composition and sexual function. Effects of androgen therapy on impotent men with normal and low free testosterone levels.
Rosenthal, B. D., May, N. R., Metro, M. J., Harkaway, R.K. and Ginsberg, P.K. Adjunctive use of AndroGel (testosterone gel) with sildenafil for the treatment of erectile dysfunction in men with androgen deficiency syndrome acquired after failure with sildenafil alone.
In fact, testosterone therapy (given to hypogonadal men who have abnormally low testosterone levels in their bodies) can actually cause testicular shrinkage, sexual dysfunction, and, in rare cases, infertility.